All my Publications

Ulrich A.K. Betz (2025)
Wissenschaft und Religion – Zwei Wege eine Wahrheit?
Springer, ISBN 978-3-031-75816-4

Ulrich A.K. Betz, Robert Garces, Norbert Beier, Sven Lindemann, Karen C. Wolff, Laura Riva, Melanie G. Kirkpatrick, Amal Gebara-Lamb, Case W. McNamara, Robert Damoiseaux, Brigitte N. Gomperts, Vaithilingaraja Arumugaswami, Marten Strand, Yongdae Gwon, Mikael Elofsson, Magnus Evander (2025)
Open Source Repurposing Reveals Broad-Spectrum Antiviral Activity of Diphenylureas
Viruses 2025, 17, 385

Chandani Sen, Tammy M. Rickabaugh, Arjit Vijey Jeyachandran, Constance Yuen, Maisam Ghannam, Abdo Durra, Adam Aziz, Kristen Castillo, Gustavo Garcia Jr., Arunima Purkayastha, Brandon Han, Felix W. Boulton, Eugene Chekler, Robert Garces, Karen C. Wolff, Laura Riva, Melanie G. Kirkpatrick, Amal Gebara-Lamb, Case W. McNamara, Ulrich A.K. Betz, Vaithilingaraja Arumugaswami, Robert Damoiseaux, Brigitte N. Gomperts (2025)
Optimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2
Respiratory Research 26:18

Ulrich A.K. Betz (2024)
Science and Religion United: The Salvation Machine
Springer, ISBN 978-3-03-155093-5

Charles A. Seipp, Brendan Michael Monks, Iuliia Karnysh, Ulrich A.K. Betz (2024)
Innovation and Team Spirit: The Magic of Science Competitions Seen through the Lens of the Compound Challenge
Angew. Chem. Int. Ed. 2024, 63, e202317338

Ulrich A.K. Betz (2024)
Curious Future Insight – Science for a Better Tomorrow
Springer, ISBN 9783031417801

Ulrich A.K. Betz, Loukik Arora, Reem A. Assal, Hatylas Azevedo, Jeremy Baldwin, Michael S. Becker, Stefan Bostock, Vinton Cheng, Tobias Egle, Nicola Ferrari, Elena K. Schneider-Futschik,  Stefan Gerhardy, Alexandra Hammes, Achim Harzheim, 
Thomas Herget, Cristina Jauset, Simon Kretschmer, Corey Lammie, Nina Kloss, Steve Marquis Fernandes, Claudia Gabriela Mitrofan, Iuliia Myrgorodska, Daniela Nedbalek, Siegfried G. Neumann, Stella Paffenholz, Laia Pascual Ponce,  Birgit Rogell, Dragana Savic, Gergana Velikova, Christian Schumacher, Nina Weisshaar, Mohammadzadeh Yahya, Joshua Y.C. Yang, Guoping Zhao (2023)
Game changers in science and technology – now and beyond
Technological Forecasting and Social Change, Volume 193, August 2023, 122588

Suzanne Acklo, Albert A. Antolin, Jose Manuel Bertolome, Hartmut Beck, Alex Bullock, Ulrich A.K. Betz, Jark Böttcher, Peter J. Brown, Menorca Chaturvedi, Alisa Crisp, Danette Daniels, Jan Dreher, Kristina Edfeldt, Aled M. Edwards, Ursula Egner, Jon Elkins, Christian Fischer, Tine Glendorf, Steven Goldberg, Ingo V. Hartung, Alexander Hillisch, Evert Homann, Stefan Knapp, Markus Köster, Oliver Krämer, Joseph Llaveria, Uta Lessel, Sven Lindemann, Lars Linderoth, Hisanori Matsui, Maurice Michel, Florian Montel, Anke Mueller-Fahrnow, Susanne Müller, Dafydd R. Owen, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Wendy Sanderson, Cora Scholten, Matthieu Schapira, Sujata Sharma, Brock Shireman, Michael Sundström, Matthew H. Todd, Claudia Tredup, Jennifer Venable, Timothy M. Wilson, Chery H. Arrowsmith (2023) 
Target 2035 – An update on private sector contributions
RSC Med. Chem. DOI 10.1039/D2MD00441K

Ulrich Betz (2022) 
Innovation – now and for generations to come.  
European Business Review, July 2022

Ulrich Betz, James Kugler, Annika Zille, Laura Matz (2022) 
Innovation powered by science, data and digital.  
Nature Portfolio https://www.nature.com/articles/d42473-022-00179-x

Suzanne Ackloo, Rima Al-awar, Rommie E. Amaro, Cheryl Arrowsmith, Hatylas Azevedo, Robert A Batey, Yoshua Bengio, Ulrich A.K. Betz, Cristian G. Bologa, John D. Chodera, Wendy D. Cornell, Ian Dunham, Gerhard F. Ecker, Kristina Edfeldt, Aled M. Edwards, Michael K. Gilson, Claudia R. Gordijo, Gerhard Hessler, Alexander Hillisch, Anders Hogner, John J. Irwin, Johanna M. Jansen, Daniel Kuhn, Andrew R. Leach, Alpha A. Lee, Uta Lessel, John Moult, Ingo Muegge, Tudor I. Oprea, Benjamin G. Perry, Patrick Riley, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Matthieu Schapira, Cora Scholten, Matthew H. Todd, Masoud Vedadi, Andrea Volkamer, Timothy M. Willson  (2022)
CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding. 
Nature Reviews Chemistry 6, 287-295

Ulrich A.K. Betz, Dragana Savic (2022)
Spells for the 21st Century
Sciracle, ISBN 979-8803197881

Susanne Müller, Suzanne Ackloo, Arij Al Chawaf, Bissan Al-Lazikani, Albert Antolin, Jonathan B. Baell, Hartmut Beck, Shaunna Beedie, Ulrich A. K. Betz, Gustavo Arruda Bezerra, Paul E. Brennan, David Brown, Peter J. Brown, Alex N. Bullock, Adrian J. Carter, Apirat Chaikuad, Mathilde Chaineau, Alessio Ciulli, Ian Collins, Jan Dreher, David Drewry, Kristina Edfeldt, Aled M. Edwards, Ursula Egner, Stephen V. Frye, Stephen M. Fuchs, Matthew D. Hall, Ingo V. Hartung, Alexander Hillisch, Stephen H. Hitchcock, Evert Homan, Natarajan Kannan, James R. Kiefer, Stefan Knapp, Milka Kostic, Stefan Kubicek, Andrew R. Leach, Sven Lindemann, Brian D. Marsden, Hisanori Matsui, Jordan L. Meier, Daniel Merk, Maurice Michel, Maxwell R. Morgan, Anke Mueller-Fahrnow, Dafydd R. Owen, Benjamin G. Perry, Saul H. Rosenberg, Kumar Singh Saikatendu, Matthieu Schapira, Cora Scholten, Sujata Sharma, Anton Simeonov, Michael Sundström, Giulio Superti-Furga, Matthew H. Todd, Claudia Tredup, Masoud Vedadi, Frank von Delft, Timothy M. Willson, Georg E. Winter, Paul Workman, Cheryl H. Arrowsmith (2021)
Target 2035 – update on the quest for a probe for every protein.
RSC Med. Chem. https://doi.org/10.1039/D1MD00228G

Adrian Elter, Desislava Yanakieva, David Fiebig, Kerstin Hallstein, Stefan Becker, Ulrich Betz and Harald Kolmar (2021)
Protease-activation of Fc-masked therapeutic antibodies to alleviate off-tumor cytotoxicity.
Front. Immunol. 12:715719. doi: 10.3389/fimmu.2021.715719

Ulrich A.K. Betz, Isabel de Paoli (2021)
Merck – curious minds dedicated to human progress.
Nature Outlook The Spinoff Prize 2021, June 2021

Ulrich A.K. Betz (2021)
United by science for a better tomorrow.
European Business Review, June 2021

Gustavo Garcia, Jr., Arun Sharma, Arunachalam Ramaiah, Chandani Sen, Arunima Pukayastha, Donald B. Kohn, Mark S. Parcells, Sebastian Beck, Heeyoung Kim, Malina A. bakowski, Melanie G. Kirkptrick, Laura Riva, Karen C. Wolff, Brandon Han, constance Yuen, David Ulmert, Prabhat K. Purbey, Phillip Scumpia, Nathan Beutler,Thomas F. Rogers, Arnab K. Chatterjee, Gülsah Gabriel, Ralf Bartenschlager, Brigitte Gomperts, Clive N. Svendsen, Ulrich A.K. Betz, Robert D. Damoiseaux, Vaithilingaraja Arumugaswami (2021)
Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.
Cell Reports 35, 108940

Jasper Bos & Ulrich A.K. Betz (2020)
Merck makes innovation happen
Nature Outlook The Spinoff Prize 2020, June 2020

J. Maier, G. Rutledge, R. Zhang, N. Kloss, L. Schuster, R. Hodos, U.A. Betz, C. Ladel (2020)
Clinical trial data analysis of the placebo effect in osteoarthritis
Osteoarthritis and Cartilage, 28, 1, S357-358, April 2020

Ulrich A.K. Betz (2020)
Science for a better tomorrow.
European Business Reviews, March 2020

Stephan Dickgiesser, Marcel Rieker, Dirk Mueller-Pompalla, Christian Schröter, Jason Tonillo, Shira Warszawski, Sabine Raab-Westphal, Stefanie Kuhn, Tim Knehans, Doreen Konning, Julia Dotterweich, Ulrich A.K. Betz, Jan Anderl, Stefan Hecht, Nicolas Rasche (2020)
Site-Specific Conjugation of Native Antibodies Using Engineered Microbial Transglutaminases
Bioconjugate Chem. 2020, 31, 4, 1070-1076

Ulrich A.K. Betz (2019)
Future Insight – From a 350th Birthday to the Start of a Global Movement
European Business Reviews, March 2019

Ulrich A.K. Betz, Frederick Betz, Rachel Kim, Brendan Monks, Fred Phillips (2019)
Surveying the future of science, technology and business – A 35 year perspective
Technology Forecasting & Social Change 144, 137-147

Ulrich A.K. Betz (2019)
Scientists, businesspeople, professional forecasters predict differing worlds of 2052
Bulletin of the Atomic Scientist, August 2019

Ulrich A.K. Betz (2019)
Curious2018 – Future Insights in Science and Technology
Springer, ISBN 3030160602

Angelo P Matos, Amy Kauffman, Christopher Vickery, Kaleb Naegeli, Lisa Strittmatter, Anastasiya Sybirna, Janneke van Blijswijk, Lorenz Adlung, Tetyana Berbasova, Jhon Enterina, Lena Eismann, Braden Tierney, Josua Jordi, Lian Zhu, Sebald Verkuijl, Lorillee Tallorin, Arne Wehling, Michael Ogden, Stephan Lammel, Maike Kober-Hasslacher, Petra Wuelfroth, Siegfried Neumann, Christian Tidona,
Ulrich A.K. Betz (2019)
Synthetic Biology Category Wins the 350th Anniversary Merck Innovation Cup
Trends in Biotechnology, November 2019

Sonja Hatz, Scott Spangler, Andrew Bender, Matthew Studham, Philipp Haselmayer, Alix MB Lacoste, Van C Willis, Richard L Martin, Harsha Gurulingappa, Ulrich Betz (2019)
Identification of pharmacodynamic biomarker hypotheses through literature analysis with IBM Watson
PLoS ONE 14(4): e0214619

Christopher Magee, Patrick Kleyn, Brendan Monks, Ulrich Betz, Subarna Basnet (2018)
Pre-existing technological core and roots for the CRISPR breakthrough
PLoS One 13 (9): e0198541

Ulrich A.K. Betz (2018)
Is the force awakening?
Technological Forecasting & Social Change, 128, 296

Ulrich A.K. Betz (2018)
Merck – fighting disease for 350 years
Nature Outlook The future of medicine, March 2018

Ulrich A.K. Betz (2018)
Breakthrough Innovation in the 21st Century
Harvard Business Review Analytic Services, March 2018

Ulrich A.K. Betz (2018)
An Innovator’s Midsummer Dream Come True
European Business Reviews, July 2018

Ulrich A.K. Betz (2018)
The Darmstadt Science Declaration: Make Science not War
Angewandte Chemie International Edition 2018, 57, 2-4

Ich bin dabei: Ulrich Betz
Nachrichten aus der Chemie 65, 409 (2017)

Ulrich A.K. Betz (2017)
Waldspaziergang mit gefallenen Blättern
In ”Wenn die Blätter von den Bäumen fallen – lyrische Anthologie“ , Johann-Friedrich Huffmann (Ed.),
p18, Edition AVRA, ISBN 978-3-946467-40-3

Ulrich A.K. Betz (2017)
Licht in den Bergen – Schatten in den Bergen
In ”Schattenspiel der Berge “ , Helmut Glatz uva,
p152, Dorante Edition, ISBN 9783744811118

Ulrich A.K. Betz (2017)
Schwarzes Nachtklagen
In ”Bibliothek Deutschsprachiger Gedichte“, Ausgewählte Werke XX
p486, Realis Verlag, ISBN 9783930048762

Ulrich A.K. Betz (2017)
Gebrochene Seelenknochen
In „Goldstaub Galaxie“, Ausgewählte Werke XX
p165, Lorbeer Verlag, ISBN 9783938969625

Vanessa Siegmund, Birgit Piater, Bijan Zakeri, Thomas Eichhorn, Frank Fischer, Carl Deutsch, Stefan Becker, Lars Toleikis, Björn Hock, Ulrich A.K. Betz, Harald Kolmar (2016)
Spontaneous Isopeptide Bond Formation as a Powerful Tool for Engineering Site-Specific Antibody-Drug Conjugates
Scientific Reports 6, Article number: 39291

Rasche N, Tonillo J, Rieker M, Becker S, Dorr B, Ter-Ovanesyan D, Betz UA, Hock B. Kolmar H (2016)
PROLink-single step circularization and purification procedure for the generation of an improved variant of human growth hormone
Bioconjug Chem. 18;27(5):1341-7

Alexander Schuhmacher, Ulrich A.K. Betz (2016)
The pharmaceutical industry is opening its R&D boundaries In: “Value Creation in the Pharmaceutical Industry”: The Critical Path to Innovation, Alexander Schuhmacher, Markus Hinder, Oliver Gassmann (Eds.), p335-362, Wiley-VCH Verlag GmbH & Co. KGaA, ISBN: 978-3-527-33913-6

Vanessa Siegmund, Birgit Piater, Ulrich A.K. Betz, Olga Avrutina, Andrea Scrima, Hans-Lothar Fuchsbauer, Harald Kolmar (2015)
Locked by design: A conformationally constrained transglutaminase tag enables efficient site-specific conjugation
Angew. Chem. Int. Ed. Engl., 54(45):13420-4

Ulrich A.K. Betz, Christian Tidona (2015)
Outcubation – where incubation meets outsourcing
Nature Biotechnology, 33, 20-21

Ulrich A.K. Betz, Paul Czodrowski, Christina Esdar, Carl Deutsch, Norbert Beier, Dirk Finsinger, Bertram Cezanne, Klaus Urbahns, Margarita Wucherer-Plietker (2014)
Fluctuating open teams (FLOT) – A new approach to boost team creativity and innovation potential
Technology Transfer and Entrepreneurship 1, 77-81

Ulrich A.K. Betz, Nino Camacho, Michael Gerards, Stefan Stremersch (2014)
Grassroots innovation: A promising innovation paradigm for pharmaceutical companies
In “Innovation and Marketing in the Pharmaceutical Industry, Emerging Practices, Research, and Policies“
Min Ding, Jehoshua Eliashberg, Stefan Stremersch (Eds.),
New York, Springer International Series in Quantitative Marketing, Vol. 20., chapter 4, ISBN 978-1-4614-7800-3

Ulrich A.K. Betz (2013)
Neue Wege zu neuen Produkten
IHKWirtschaftsforum, 07/2013, 136

Yasunobu Arima, Masaya Harada, Daisuke Kamimura, Jin-Haeng Park, Fuminori Kawano, Fiona E. Yull, Tadafumi Kawamoto, Yoichiro Iwakura, Ulrich A.K. Betz, Gabriel Marquez, Timothy S. Blackwell, Yoshinobu Ohira, Toshio Hirano, Masaaki Murakami (2012)
Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier
Cell, 148, 447-457

Merck Serono Innovationsmanager Ulrich Betz im Gespräch
Innovationsmanager 19, 74-75, Juni 2012

Ulrich A.K. Betz (2011)
Portfolio management in early stage drug discovery – a traveler’s guide through uncharted territory
Drug Discovery Today, 16, 609-618.

Ulrich A.K. Betz (2011)
Open Innovation, Crowd Sourcing und Open Source – Neue Wege zum Erfolg
In ”Science4Life Venture Cup 2011 – Science4Life die Gründerinitiative für Life Sciences und Chemie.“ p35, Geschäftsstelle Science4Life e.V.

Taking innovation to a new level
PharmaVoice, 88, October 2011

Ulrich A.K. Betz (2011)
What fantasy role-playing games can teach your children (or even you)
British Journal of Educational Technology 42, E117-121

Ulrich A.K. Betz (2010)
Sonne in deinem Gesicht
In ”Die Literareon Lyrik-Bibliothek“ Band XI, Anja Zimmermann (Ed.),
p16, Herbert Utz Verlag, ISBN 978-3-8316-1469-1

Ulrich A.K. Betz, Siegfried Neumann (2009)
The Marco Polo project
In „Fallstudien zum Innovationsmanagement“ Jan Hendrik Fisch, Jan-Michael Roß (Eds.),
p93-110, Gabler, ISBN 978-3-8349-1047-9

Atsumi, M. Sato, D. Kamimura, A. Moroi,Y. Iwakura, U.A.K. Betz, A. Yoshimura, M. Nishihara, T. Hirano, M. Murakami (2008)
IFNg expression in CD8+ cells regulated by IL-6 signal is involved in superantigen-mediated CD4+ T-cell death
Int. Immunol., 21, 73-80

Nishihara, H. Ogura, N. Ueda, M. Tsuruoka, C. Kitabayashi, F. Tsuji, H. Aono, K. Ishihara, E. Huseby, U.A. Betz, M. Murakami, T. Hirano (2007)
IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state
Int. Immunol., 19, 695-702

P.E. Forni, C. Scuoppo, I. Imayoshi, R. Taulli, W. Dastru, V. Sala, U.A. Betz, P. Muzzi, D. Martinuzzi, A.E. Vercelli, R. Kageyama, C. Ponzetto (2006)
High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly
J. Neurosci., 26, 9593-9602

Kehlenbeck, U. Betz, A. Birkmann, B. Fast, A. Göller, K. Henninger, T. Lowinger, D. Marrero, A. Paessens, D. Paulsen, V. Pevzner, R. Schohe-Loop, H. Tsujishita, R. Welker, J. Kreuter, H. Rübsamen-Waigmann, F. Dittmer (2006)
Dihydroxythiophenes are novel potent inhibitors of human immunodeficiency virus integrase with a diketo acid-like pharmacophore
J. Virol., 80, 6883-6894

Ulrich A.K. Betz, Ronald Farquhar, Karl Ziegelbauer (2005)
Genomics: Success or failure to deliver drug targets?
Curr. Opin. Chem. Biol. Rev. 9, 1-5

Ulrich A.K. Betz (2005)
How many genomics targets can a portfolio afford?
Drug Discovery Today, 10, 1057-1063

Ulrich A.K. Betz, Timo Fleßner (2004)
The future of drug discovery
In ”The Future of Pharma R&D“ Harald Pacl, Gunter Festel, Günther Wess (Eds.),
p47-51, Festel Capital, ISBN 3-00-014012-3

Konrad L. Streetz, Torsten Wüstefeld, Christian Klein, Karl-Josef Kallen, Francois Tronche, Ulrich A.K. Betz, Günther Schütz, Michael P. Manns, Werner Müller, Christian Trautwein (2003)
Lack of gp130 expression in hepatocytes promotes liver injury
Gastroenterology 125(2): 532-543

Torsten Wuestefeld, Christian Klein, Konrad L. Streetz, Ulrich Betz, Jörg Lauber, Jan Buer, Michael P. Manns, Werner Müller, Christian Trautwein (2003)
Interleukin-6/Glycoprotein 130-dependent pathways are protective during liver regeneration.
J. Biol. Chem. 278(13), 11281-11288

Wuestefeld, C. Klein, K.L. Streetz, U. Betz, W. Müller, M.P. Manns (2003)
gp130-dependent signaling is important to activate antiapoptotic pathways during liver regeneration
J. Hepatol. 38, 87

Torsten Wuestefeld, Christian Klein, Konrad L. Streetz, Ulrich Betz, Werner Müller, Michael P. Manns (2002)
gp130-dependent signaling induces acute phase gene expression and is crucial for survival after two-thirds partial hepatectomy
J. Hepatol. 36, 10

Mark Hallonet, Klaus H. Kaestner, Luis Martin-Parras, Hiroshi Sasaki, Ulrich A.K. Betz, Siew-Lan Ang (2002)
Maintenance of the specification of the anterior definitive endoderm and forebrain depends on the axial mesendoderm: A study using HNF3ß conditional mutants
Dev. Biol. 243(1), 20-33

Gerald Kleymann, Rüdiger Fischer, Ulrich A.K. Betz, Martin Hendrix, Wolfgang Bender, Udo Schneider, Gabriele Handke, Peter Eckenberg, Guy Hewlett, Veniamin Pevzner, Olaf Weber, Judith Baumeister, Kerstin Henninger, Jörg Keldenich, Axel Jensen, Jörg Kolb, Ute Bach, Andreas Popp, Jutta Mäßen, Isabelle Frappa, Dieter Haebich, Oswald Lockhoff, Helga Rübsamen-Waigmann (2002)
New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease
Nature Medicine 8(4), 392-398

Ulrich A.K. Betz, Rüdiger Fischer, Gerald Kleymann, Martin Hendrix, Helga Rübsamen-Waigmann (2002)
Potent in vivo antiviral activity of the new herpes simplex virus primase-helicase inhibitor BAY 57-1293
Antimicrobial Agents and Chemotherapy 46(6), 1766-1772

Toni Alonzi, Gayle Middleton, Sean Wyatt, Vladimir Buchman, Ulrich A.K. Betz, Werner Müller, Piero Musiani, Valeria Poli, Alun M. Davies (2001)
Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of cytokines on sensory neurons
Molecular and Cellular Neuroscience 18, 270-282

K.L. Streetz, T. Wuestefeld, H. Kreipe, F. Tronche, G. Schuetz, U. Betz, W. Mueller, M. Manns, C. Trautwein (2001)
The role of gp130 in the liver – differentiation between hepatocytes and non-parenchymal liver cells in CCL4 induced liver injury
J. Hepatol. 34, 7

Wuestefeld, K.L. Streetz, U. Betz, W. Mueller, M.P. Manns (2001)
After partial hepatectomy gp130 is involved in the priming phase of hepatocytes, but not essential for liver regeneration.
J. Hepatol. 34, 83

Gloria Esposito, Gemma Texido, Ulrich A.K. Betz, Hua Gu, Werner Müller, Ulf Klein, Klaus Rajewsky (2000)
Mice reconstituted with DNA polymerase ß-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally
Proc. Natl. Acad. Sci. USA 97, 1166-1171

Hisao Hirota, Ju Chen, Ulrich A.K. Betz, Yusu Gu, John Ross Jr., Werner Müller, Klaus Rajewsky, Kenneth R. Chien (1999)
Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
Cell 97, 189-198

Ulrich A.K. Betz, Klaus Rajewsky, Werner Müller (1998)
Regulated expression of gp130 and IL6 receptor gamma chain in T cell maturation and activation.
Int. Immunol. 10, 1175-1184

Ulrich A.K. Betz, Wilhelm Bloch, Maries van den Broek, Kanji Yoshida, Tetsuya Taga, Tadamitsu Kishimoto, Klaus Addicks, Klaus Rajewsky, Werner Müller (1998)
Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic and pulmonary defects
J. Exp. Med. 188, 1955-1965

Ulrich A.K. Betz (1998)
Konditionale Cre/loxP-katalysierte Genveränderung in der Maus zur Aufklärung der Rolle des Zytokinrezeptors gp130 in vivo.
Dissertationsschrift, Köln

Ulrich A.K. Betz (1997)
Abstract: Generation and analysis of conditional mouse mutants.
FASEB J 11, A1123

U.A.K. Betz, T. Taga, T. Kishimoto, K. Rajewsky, W. Müller (1997)
Abstract: Conditional inactivation of gp130 in mice
Immunology Letters 56, 352

Ulrich A.K. Betz (1997)
Generation and analysis of conditional mutant mice.
Res. Immunol. 148, 475-480

Klaus Rajewsky, Hua Gu, Ralf Kühn, Ulrich A.K. Betz, Werner Müller,
Jürgen Roes, Frieder Schwenk (1996)
Conditional Gene Targeting
J. Clin. Invest. 98, 600-603

Klaus Rajewsky, Hua Gu, Ralf Kühn, Ulrich A.K. Betz, Werner Müller,
Jürgen Roes, Frieder Schwenk (1996)
Conditional Gene Targeting
J. Clin. Invest. 98(Suppl.), S51-S53

Ulrich A.K. Betz, Christian A.J. Voßhenrich, Klaus Rajewsky, Werner Müller (1996)
Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination
Curr. Biol. 6, 1307-1316

Ulrich A.K. Betz (1994)
Haupthistokompatibilitätskomplex Klasse I Gene des lebenden Fossils
Latimeria chalumnae.
Diplomarbeit
Tübingen

Ulrich A.K. Betz, Werner E. Mayer, Jan Klein (1994)
Major histocompatibility complex class I genes of the coelacanth
Latimeria chalumnae
Proc. Natl. Acad. Sci. USA 91, 11065-11069

Interviews

Andy Tay (2022)
Science competitions can help to catapult your science into the real world.
Nature, Career Feature, February 28th 2022

Merck: Mit neuen Ideen zum führenden Wissenschafts- und Technologieunternehmen des 21. Jahrhunderts.
CHEManager 22.02.2022

Patents

WO-002023222332
Ulrich Betz, Sven Lindemann (2023)
Diphenyl ureas for the treatment of viral infections

WO-002022090063
Ulrich Betz, Thomas Fuchss (2022)
ATR inhibitors for the use in the treatment of viral infections

WO-002022079250
Ulrich Betz, Lars Burgdorf, Dirk Finsinger, Markus Klein, Sven Carsten Poetzsch (2022)
Compounds for the treatment of viral infections

WO-002022063869
Ulrich Betz, Gordon Philipp Otto (2022)
Compounds for the treatment of viral infections

WO-002022058323
Ulrich Betz (2022)
Compounds for the treatment of viral infections

WO-002021254978
Ulrich Betz, Thomas Fuchss (2021)
Compounds for the treatment of viral infections

WO002021254982
Ulrich Betz (2021)
Compounds for the treatment of viral infections

WO002022058323
Ulrich Betz (2021)
Compounds for the treatment of viral infections

WO002022063869
Ulrich Betz, Gordon Philipp Otto (2022)
Compounds for the treatment of viral infections

WO002022079250A1
Ulrich Betz, Lars Burgdorf, Dirk Finsinger, Markus Klein, Sven Carsten Poetzsch (2022)
Compounds for the treatment of viral infections

WO002022090063A1
Ulrich Betz, Thomas Fuchss (2022)
ATR inhibitors for the use in the treatment of viral infections

WO-002017025179
Ulrich Betz, Harald Kolmar, Birgit Piater, Vanessa Siegmund (2017)
A transglutaminase tag for efficient site-specific bioconjugation

WO-2009135583
Norbert Beier, Wolfgang Scholz, Ulrich Betz, Marian Brändle (2009)
Pharmaceutical composition comprising Rimeporide for treating diseases associated with insulin resistance and beta-cell dysfunction

WO-2006092209
Helmuth Van Es, Marlijn Van Zutphen, Emir Mesic, Ulrich Betz, Donatella D’Urso, Petros Gatsios, Michael Seewald, Jochen Strayle (2005)
Novel targets and compounds useful in the treatment of a cardiovascular disorder, dyslipidemia and Atherosclerosis, and methods to identify such compounds

WO-2006108584
Anne Grabner, Michael Hannus, Ulrich Betz, Donatella D’Urso, Peter Kolkhof, Michael Seewald, Jochen Strayle (2005)
Human marker genes and agents for diagnosis, treatment and prophylaxis of cardiovascular disorders and artherosclerosis

WO-2005025617
Ulrich Betz, Martin Radtke (2003)
Methods and compositions for treating Herpes infections

WO-2004096778
Tobias Wunberg, Judith Baumeister, Ulrich Betz, Mario Jeske, Thomas Lampe, Susanne Nikolic, Jürgen Reefschläger, Rudolf Schohe-Loop, Frank Süßmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Jörg Keldenich, Dieter Lang, Peter Nell (2003)
Substituierte Dihydrochinazoline mit antiviralen Eigenschaften

WO-2004072048
Tobias Wunberg, Judith Baumeister, Ulrich Betz, Mario Jeske, Gerald Kleymann, Thomas Lampe, Susanne Nikolic, Jürgen Reefschläger, Rudolf Schohe-Loop, Frank Süßmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Jörg Keldenich, Thomas Krämer, Peter Nell, Tse-I Lin (2003)
2-(3-Phenyl-2-Piperazinyl-3,4-Dihydroquinazoline-4-yl) acetic acids as anti-viral agents, especially against cytomegalo viruses

WO-2004060860
Ulrich Betz, Guy Hewlett, Gerald Kleymann, Thomas Lampe, Tsi-I Lin, Susanne Nikolic, Jürgen Reefschläger, Tobias Wunberg, Holger Zimmermann, Franz Zumpe, Wolfgang Bender, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Rudolf Schohe-Loop (2004)
Methode zur Inhibition der Replikation von Herpesviren

WO-2004052363
Tobias Wunberg, Judith Baumeister, Ulrich Betz, Axel Jensen, Susanne Nikolic, Holger Zimmermann, Franz Zumpe, Rolf Grosser, Wolfgang Bender, Kerstin Henninger, Guy Hewlett, Jörg Keldenich (2003)
Oxazolidinones used as antiviral agents, in particular for fighting against Cytomegalovirus

DE-0010226048
Ulrich Betz, Johannes-Peter Stasch, Rüdiger Fischer, Martin Hendrix, Rudolf Schohe-Loop (2003)
Thiazolylsulfonamide

WO-2003097595
Tobias Wunberg, Judith Baumeister, Ulrich Betz, Axel Jensen, Susanne Nikolic, Jürgen Reefschläger, Holger Zimmermann, Franz Zumpe, Rolf Grosser, Gerald Kleymann, Wolfgang Bender, Kerstin Henninger, Guy Hewlett, Jörg Keldenich (2002)
Lactams Used as Anti-Viral Agents

DE-0010210319
Wolfgang Bender, Ulrich Betz, Gerald Kleymann, Judith Baumeister, Peter Eckenberg, Rüdiger Fischer, Gabriele Handke-Ergüden, Martin Hendrix, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Jürgen Reefschläger, Udo Schneider, Thorsten Schmidt, Olaf Weber (2002)
Thiazolylcarbonyl-Derivate

WO-2003089421
Tobias Wunberg, Ulrich Betz, Judith Baumeister, Axel Jensen, Susanne Nikolic, Jürgen Reefschläger, Holger Zimmermann, Franz Zumpe, Rolf Grosser, Gerald Kleymann, Wolfgang Bender, Kerstin Henninger, Guy Hewlett, Jörg Keldenich (2002)
Antiviral Lactone Ureas

WO-2003064394
Tobias Wunberg, Ulrich Betz, Gerald Kleymann, Susanne Nikolic, Jürgen Reefschläger, Rudolf Schohe-Loop, Holger Zimmermann, Franz Zumpe, Wolfgang Bender, Kerstin Henninger, Guy Hewlett, Axel Jensen, Jörg Keldenich (2002)
5-Ring Heterocycles used as Antiviral Agents

DE-0010131128
Gerald Kleymann, Rüdiger Fischer, Ulrich Betz, Wolfgang Bender, Peter Eckenberg, Gabriele Handke-Ergüden, Martin Hendrix, Udo Schneider, Rudolf Schohe-Loop, Judith Baumeister, Olaf Weber, Kerstin Henninger, Axel Jensen, Jörg Keldenich (2001)
Sekundäre Sulfonamide

DE-0010129717
Gerald Kleymann, Ulrich Betz, Rüdiger Fischer, Martin Hendrix, Wolfgang Bender, Peter Eckenberg, Gabi Handke, Udo Schneider, Rudolf Schohe-Loop, Judith Baumeister, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Olaf Weber (2001)
Kombinationspräparate zur Herpesbehandlung

WO-2003007946
Rüdiger Fischer, Ulrich Betz, Martin Hendrix, Gerald Kleymann, Rudolf Schohe-Loop, Judith Baumeister, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Udo Schneider, Olaf Weber (2001)
Secondary 1,3-thiazole-5-yl-sulfonamide derivatives and their use as antiviral agents

WO-2003000260
Rudolf Schohe-Loop, Ulrich Betz, Rüdiger Fischer, Martin Hendrix, Gerald Kleymann, Judith Baumeister, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Udo Schneider, Olaf Weber (2001)
Substituierte Cycloalkylsulfonamide

WO-2003002541
Tobias Wunberg, Ulrich Betz, Sabine Hallenberger, Gerald Kleymann, Thomas Lampe, Susanne Nikolic, Jürgen Reefschläger, Franz Zumpe, Marcus Bauser, Wolfgang Bender, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Axel Jensen, Jörg Keldenich, Holger Zimmermann (2001)
Pyridazinone als antivirale Mittel und neue Stoffe

DE-0010129716
Ulrich Betz, Dieter Rehn, Tobias Laich, Gerald Kleymann (2001)
Kombinationspräparate zur Herpesbehandlung

WO-2003000259
Ulrich Betz, Tobias Laich, Wolfgang Bender, Rüdiger Fischer, Martin Hendrix, Gerald Kleymann (2001)
Topical Application of Thiazolylamides

DE-0010044328
Wolfgang Bender, Gerald Kleymann, Ulrich Betz, Judith Baumeister, Peter Eckenberg, Rüdiger Fischer, Gabriele Handke, Martin Hendrix, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Udo Schneider, Olaf Weber (2000)
Thiazolylcarbonyl-Derivate

WO-2002030468
Martin Vollmer, Joachim Simon, Ulrich Betz, Phil Scuderi (2001)
Complexes for transferring nucleic acids into cells

WO-2002012211
Rüdiger Fischer, Gerald Kleymann, Ulrich Betz, Judith Baumeister, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Martin Hendrix, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Udo Schneider, Olaf Weber (2000)
Inverse Thiazolyl Amide Derivatives

WO-2002020014
Gerald Kleymann, Rüdiger Fischer, Martin Hendrix, Guy Hewlett, Veniamin Pevzner, Ulrich Betz, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Udo Schneider, Olaf Weber, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Judith Baumeister (2000)
Incompetitive inhibitors of helicase-primase

WO-2001096874
Gerald Kleymann, Ulrich Betz, Rüdiger Fischer, Martin Hendrix, Guy Hewlett, Veniamin Pevzner (2000)
Method for identifying compounds with anti-herpes activity

DE-0010030376
Ulrich Betz, Gerald Kleymann, Olaf Weber, Emanuel Lohrmann (2000)
Neues Verfahren zum Auffinden neuer Wirkstoffe

WO-2001047904
Rüdiger Fischer, Gerald Kleymann, Ulrich Betz, Judith Baumeister, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Martin Hendrix, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Udo Schneider, Olaf Weber (2000)
Thiazolyl Amide Derivatives

WO-2000076966
Gabriele Handke, Judith Baumeister, Wolfgang Bender, Ulrich Betz, Michael Brands, Peter Eckenberg, Rüdiger Fischer, Martin Hendrix, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Gerald Kleymann, Jutta Mäßen, Udo Schneider, Olaf Weber (1999)
Indolinyl Amide Derivatives

WO-2000053591
Rüdiger Fischer, Gerald Kleymann, Judith Baumeister, Wolfgang Bender, Ulrich Betz, Peter Eckenberg, Gabriele Handke, Martin Hendrix, Udo Schneider, Olaf Weber, Kerstin Henninger, Axel Jensen, Jörg Keldenich (1999)
Thiazolyl urea derivatives and their utilization as antiviral agents